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A method to culture human alveolar rhabdomyosarcoma cell lines as rhabdospheres demonstrates an enrichment in stemness and Notch signaling

The development of three-dimensional cell culture techniques has allowed cancer researchers to study the stemness properties of cancer cells in in vitro culture. However, a method to grow PAX3-FOXO1 fusion-positive rhabdomyosarcoma (FP-RMS), an aggressive soft tissue sarcoma of childhood, has to dat...

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Detalles Bibliográficos
Autores principales: Slemmons, Katherine K., Deel, Michael D., Lin, Yi-Tzu, Oristian, Kristianne M., Kuprasertkul, Nina, Genadry, Katia C., Chen, Po-Han, Ashley Chi, Jen-Tsan, Linardic, Corinne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888706/
https://www.ncbi.nlm.nih.gov/pubmed/33372065
http://dx.doi.org/10.1242/bio.050211