Neural crest-specific loss of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction and disordered breathing, modeling obstructive sleep apnea

Pediatric obstructive sleep apnea (OSA), a relatively common sleep-related breathing disorder affecting ∼1-5% of children, is often caused by anatomical obstruction and/or collapse of the nasal and/or pharyngeal airways. The resulting sleep disruption and intermittent hypoxia lead to various systemi...

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Detalles Bibliográficos
Autores principales: Baddam, Pranidhi, Biancardi, Vivian, Roth, Daniela M., Eaton, Farah, Thereza-Bussolaro, Claudine, Mandal, Rupasri, Wishart, David S., Barr, Amy, MacLean, Joanna, Flores-Mir, Carlos, Pagliardini, Silvia, Graf, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888714/
https://www.ncbi.nlm.nih.gov/pubmed/33431521
http://dx.doi.org/10.1242/dmm.047738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888714/
https://www.ncbi.nlm.nih.gov/pubmed/33431521
http://dx.doi.org/10.1242/dmm.047738

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