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Genomic profiling of native R loops with a DNA-RNA hybrid recognition sensor

An R loop is a unique triple-stranded structure that participates in multiple key biological processes and is relevant to human diseases. Accurate and comprehensive R loop profiling is a prerequisite for R loops studies. However, current R loop mapping methods generate large discrepancies, therefore...

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Detalles Bibliográficos
Autores principales: Wang, Kang, Wang, Honghong, Li, Conghui, Yin, Zhinang, Xiao, Ruijing, Li, Qiuzi, Xiang, Ying, Wang, Wen, Huang, Jian, Chen, Liang, Fang, Pingping, Liang, Kaiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888926/
https://www.ncbi.nlm.nih.gov/pubmed/33597247
http://dx.doi.org/10.1126/sciadv.abe3516