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3D microscopy and deep learning reveal the heterogeneity of crown-like structure microenvironments in intact adipose tissue
Crown-like structures (CLSs) are adipose microenvironments of macrophages engulfing adipocytes. Their histological density in visceral adipose tissue (VAT) predicts metabolic disorder progression in obesity and is believed to initiate obesity comorbidities. Here, we use three-dimensional (3D) light...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888944/ https://www.ncbi.nlm.nih.gov/pubmed/33597245 http://dx.doi.org/10.1126/sciadv.abe2480 |