Cargando…

3D microscopy and deep learning reveal the heterogeneity of crown-like structure microenvironments in intact adipose tissue

Crown-like structures (CLSs) are adipose microenvironments of macrophages engulfing adipocytes. Their histological density in visceral adipose tissue (VAT) predicts metabolic disorder progression in obesity and is believed to initiate obesity comorbidities. Here, we use three-dimensional (3D) light...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geng, Junlong, Zhang, Xiaohui, Prabhu, Suma, Shahoei, Sayyed Hamed, Nelson, Erik R., Swanson, Kelly S., Anastasio, Mark A., Smith, Andrew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888944/ https://www.ncbi.nlm.nih.gov/pubmed/33597245 http://dx.doi.org/10.1126/sciadv.abe2480

Ejemplares similares

SAT-332 ERRα Modulates Genes of Importance to Macrophage Biology and Breast Cancer Progression
por: Cler, Samuel, et al.
Publicado: (2019)

MICROBIOLOGICAL AND MICROSCOPIC ANALYSIS OF THE PULP OF NON-VITAL TRAUMATIZED TEETH WITH INTACT CROWNS
por: Bruno, Kely Firmino, et al.
Publicado: (2009)

OR05-01 Small Heterodimer Partner Modulates Antigen Presenting Myeloid Cells to Impair Regulatory T Cell Expansion, Promoting Anti-Tumor Immunity in Models of Breast Cancer
por: Shahoei, Sayyed Hamed, et al.
Publicado: (2020)

OR05-01 Myeloid Cell Intrinsic NR0B2 Inhibits Regulatory T Cell Expansion Within The Tumor Microenvironment: Potential Novel Strategy For Breast Cancer Immunotherapy
por: Vidana Gamage, Hashni Epa, et al.
Publicado: (2023)

Fluorescent Microscopy-Based Detection of Chitin in Intact Drosophila melanogaster
por: Flaven-Pouchon, J., et al.
Publicado: (2022)

B lymphocytes in human subcutaneous adipose crown-like structures
por: McDonnell, Marie E., et al.
Publicado: (2012)

Vibrational microscopy and imaging of skin: from single cells to intact tissue
por: Zhang, Guojin, et al.
Publicado: (2006)

Tracking X-ray microscopy for alveolar dynamics in live intact mice
por: Chang, Soeun, et al.
Publicado: (2013)

Intact innervation is essential for diet-induced recruitment of brown adipose tissue
por: Fischer, Alexander W., et al.
Publicado: (2019)

In vivo three-photon microscopy of subcortical structures within an intact mouse brain
por: Horton, Nicholas G., et al.
Publicado: (2013)

Intact myocardial preparations reveal intrinsic transmural heterogeneity in cardiac mechanics
por: Pitoulis, Fotios G., et al.
Publicado: (2020)

In vitro activity of vancomycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci
por: El-Azizi, Mohamed, et al.
Publicado: (2005)

Brown Adipose Tissue Prevalence Is Lower in Obesity but Its Metabolic Activity Is Intact
por: Kulterer, Oana C., et al.
Publicado: (2022)

Variable-angle total internal reflection fluorescence microscopy of intact cells of Arabidopsis thaliana
por: Wan, Yinglang, et al.
Publicado: (2011)

Studying the Stoichiometry of Epidermal Growth Factor Receptor in Intact Cells using Correlative Microscopy
por: Peckys, Diana B., et al.
Publicado: (2015)

Ultraprecise single-molecule localization microscopy enables in situ distance measurements in intact cells
por: Coelho, Simao, et al.
Publicado: (2020)

Revealing the ultrastructure of the membrane pores of intact Serratia marcescens cells by atomic force microscopy
por: Lin, Yu-Chun, et al.
Publicado: (2019)

Preparation of the intact rodent organ of Corti for RNAscope and immunolabeling, confocal microscopy, and quantitative analysis
por: Reijntjes, Daniel O.J., et al.
Publicado: (2021)

Obesity and Breast Cancer: The Role of Crown-Like Structures in Breast Adipose Tissue in Tumor Progression, Prognosis, and Therapy
por: Faria, Sara Socorro, et al.
Publicado: (2020)

A Multi-Phasic Perspective of the Intact Permeability of the Heterogeneous Argillaceous Cobourg Limestone
por: Selvadurai, A. P. S.
Publicado: (2019)

Spatial molecular-dynamically ordered NMR spectroscopy of intact bodies and heterogeneous systems
por: Ito, Kengo, et al.
Publicado: (2020)

The Preparation of Roots for Crowning and Gold Crowns
por: Campbell,
Publicado: (1895)

Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis
por: Fenzl, Anna, et al.
Publicado: (2020)

A clearing-free protocol for imaging intact whole adipose tissue innervation in mice
por: Willows, Jake W., et al.
Publicado: (2022)

On Crowns
por: Genese, David
Publicado: (1893)

A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms
por: Shu, Xiaokun, et al.
Publicado: (2011)

Stochastic Optical Reconstruction Microscopy Imaging of Microtubule Arrays in Intact Arabidopsis thaliana Seedling Roots
por: Dong, Bin, et al.
Publicado: (2015)

Super-Resolution Microscopy Using Standard Fluorescent Proteins in Intact Cells under Cryo-Conditions
por: Kaufmann, Rainer, et al.
Publicado: (2014)

Combined transmission, dark field and fluorescence microscopy for intact, 3D tissue analysis of biopsies
por: Boamfa, Marius I., et al.
Publicado: (2020)

Laser scanning reflection-matrix microscopy for aberration-free imaging through intact mouse skull
por: Yoon, Seokchan, et al.
Publicado: (2020)

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma
por: DeCordova, Syreeta, et al.
Publicado: (2020)

Crown-Like Structures in Breast Adipose Tissue: Early Evidence and Current Issues in Breast Cancer
por: Maliniak, Maret L., et al.
Publicado: (2021)

Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA
por: Dai, Bo, et al.
Publicado: (2011)

Importance of the Microenvironment and Mechanosensing in Adipose Tissue Biology
por: Lecoutre, Simon, et al.
Publicado: (2022)

Genetic Heterogeneity, Tumor Microenvironment and Immunotherapy in Triple-Negative Breast Cancer
por: Kudelova, Eva, et al.
Publicado: (2022)

Direct Imaging of Protein Organization in an Intact Bacterial Organelle Using High-Resolution Atomic Force Microscopy
por: Kumar, Sandip, et al.
Publicado: (2016)

Heterogeneity of human adipose blood flow
por: Levitt, David G
Publicado: (2007)

Deciphering White Adipose Tissue Heterogeneity
por: Luong, Quyen, et al.
Publicado: (2019)

Novel insights into adipose tissue heterogeneity
por: Wang, Tongtong, et al.
Publicado: (2021)

HIV-Exposed Seronegative Sex Workers Express Low T-Cell Activation and an Intact Ectocervical Tissue Microenvironment
por: Röhl, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8spd2p0mobjpc868bbiqcijme6