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NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation

The epidermis regenerates continually to maintain a protective barrier at the body’s surface composed of differentiating keratinocytes. Maturation of this stratified tissue requires that keratinocytes undergo wholesale organelle degradation upon reaching the outermost tissue layers to form compacted...

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Detalles Bibliográficos
Autores principales: Simpson, Cory L., Tokito, Mariko K., Uppala, Ranjitha, Sarkar, Mrinal K., Gudjonsson, Johann E., Holzbaur, Erika L.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888979/
https://www.ncbi.nlm.nih.gov/pubmed/33535046
http://dx.doi.org/10.1016/j.celrep.2021.108689