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NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation
The epidermis regenerates continually to maintain a protective barrier at the body’s surface composed of differentiating keratinocytes. Maturation of this stratified tissue requires that keratinocytes undergo wholesale organelle degradation upon reaching the outermost tissue layers to form compacted...
Autores principales: | Simpson, Cory L., Tokito, Mariko K., Uppala, Ranjitha, Sarkar, Mrinal K., Gudjonsson, Johann E., Holzbaur, Erika L.F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7888979/ https://www.ncbi.nlm.nih.gov/pubmed/33535046 http://dx.doi.org/10.1016/j.celrep.2021.108689 |
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