IgG4 induces tolerogenic M2-like macrophages and correlates with disease progression in colon cancer

IgG4 subclass antibodies are expressed in alternative Th2 environments featuring high IL-10 expression, including several solid tumors such as melanoma. To induce tolerance, allergen immunotherapy mediates antibody class switching from pro-inflammatory IgE to anti-inflammatory IgG4. We previously re...

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Detalles Bibliográficos
Autores principales: Jordakieva, Galateja, Bianchini, Rodolfo, Reichhold, Daniel, Piehslinger, Jakob, Groschopf, Alina, Jensen, Sebastian A., Mearini, Ettore, Nocentini, Giuseppe, Crevenna, Richard, Zlabinger, Gerhard J., Karagiannis, Sophia N., Klaus, Alexander, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889146/
https://www.ncbi.nlm.nih.gov/pubmed/33628623
http://dx.doi.org/10.1080/2162402X.2021.1880687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889146/
https://www.ncbi.nlm.nih.gov/pubmed/33628623
http://dx.doi.org/10.1080/2162402X.2021.1880687

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