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Activin A backs-up TGF-ß to promote regulatory T cells
The mechanisms accountable for the infiltration of regulatory T cells into an irradiated tumor remain elusive. In our recent study, we demonstrate that activin A promotes regulatory T cells in tumors, and impairs anti-tumor immune responses induced by radiotherapy and TGF-β blockade. Dual blockade o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889161/ https://www.ncbi.nlm.nih.gov/pubmed/33628624 http://dx.doi.org/10.1080/2162402X.2021.1883288 |