Long non-coding RNA HOTAIR knockdown alleviates gouty arthritis through miR-20b upregulation and NLRP3 downregulation

This study aimed to determine the mechanism underlying the regulation of gout by the HOX transcript antisense RNA (HOTAIR) long non-coding RNA (lncRNA). The expression levels of HOTAIR, miR-20b, and Nlrp3 were estimated by qRT-PCR and western blotting. The methylation level of HOTAIR was detected by...

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Detalles Bibliográficos
Autores principales: Liu, Ya-Fei, Xing, Guo-Lan, Chen, Zhe, Tu, Sheng-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889175/
https://www.ncbi.nlm.nih.gov/pubmed/33467979
http://dx.doi.org/10.1080/15384101.2021.1874696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889175/
https://www.ncbi.nlm.nih.gov/pubmed/33467979
http://dx.doi.org/10.1080/15384101.2021.1874696

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