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Long non-coding RNA HOTAIR knockdown alleviates gouty arthritis through miR-20b upregulation and NLRP3 downregulation
This study aimed to determine the mechanism underlying the regulation of gout by the HOX transcript antisense RNA (HOTAIR) long non-coding RNA (lncRNA). The expression levels of HOTAIR, miR-20b, and Nlrp3 were estimated by qRT-PCR and western blotting. The methylation level of HOTAIR was detected by...
Autores principales: | Liu, Ya-Fei, Xing, Guo-Lan, Chen, Zhe, Tu, Sheng-Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889175/ https://www.ncbi.nlm.nih.gov/pubmed/33467979 http://dx.doi.org/10.1080/15384101.2021.1874696 |
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