One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics

T-cell engaging biologics is a class of novel and promising immune-oncology compounds that leverage the immune system to eradicate cancer. Here, we compared and contrasted a bispecific diabody-Fc format, which displays a relatively short antigen-binding arm distance, with our bispecific IgG platform...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Yang, Fan, Wang, Carole, Narula, Jatin, Pascua, Edward, Ni, Irene, Ding, Sheng, Deng, Xiaodi, Chu, Matthew Ling-Hon, Pham, Amber, Jiang, Xiaoyue, Lindquist, Kevin C., Doonan, Patrick J., Van Blarcom, Tom, Yeung, Yik Andy, Chaparro-Riggers, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889206/
https://www.ncbi.nlm.nih.gov/pubmed/33557687
http://dx.doi.org/10.1080/19420862.2020.1871171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889206/
https://www.ncbi.nlm.nih.gov/pubmed/33557687
http://dx.doi.org/10.1080/19420862.2020.1871171

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