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The antihypertensive effect of irbesartan in spontaneously hypertensive rats is associated with improvement of the leptin–adiponectin imbalance

Objective: This study aimed to investigate whether the antihypertensive effect of irbesartan (IRB) in spontaneously hypertensive rats (SHR) was achieved through improvement of insulin resistance and adjustment of the LPN–APN imbalance.Methods:SHR rats were divided into SHAM, SHR-A and SHR-I group(8...

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Detalles Bibliográficos
Autores principales: Weng, Junting, Chen, Min, Guo, Rongjie, Yang, Shuzhen, Liu, Danjuan, Fang, Dexiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889210/
https://www.ncbi.nlm.nih.gov/pubmed/33570444
http://dx.doi.org/10.1080/21623945.2021.1886409