Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation

Discovering of new anticancer agents with potential activity against tubulin polymerisation is still a promising approach. Colchicine binding site inhibitors are the most relevant anti-tubulin polymerisation agents. Thus, new quinoline derivatives have been designed and synthesised to possess the sa...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagras, Mohamed, El Deeb, Moshira A., Elzahabi, Heba S. A., Elkaeed, Eslam B., Mehany, Ahmed B. M., Eissa, Ibrahim H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889231/
https://www.ncbi.nlm.nih.gov/pubmed/33588683
http://dx.doi.org/10.1080/14756366.2021.1883598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889231/
https://www.ncbi.nlm.nih.gov/pubmed/33588683
http://dx.doi.org/10.1080/14756366.2021.1883598

Ejemplares similares