Inhibition of indoleamine 2,3-dioxygenase 1 synergizes with oxaliplatin for efficient colorectal cancer therapy

We investigated the immunogenic cell death provoked by oxaliplatin (OXA) and the involvement of OXA-induced immunosuppression in colorectal cancer. Immune-proficient or -deficient mice were employed to evaluate the therapeutic effects of OXA. Immunogenic cell death was characterized by cell-surface...

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Detalles Bibliográficos
Autores principales: Miao, Xiaofei, Zhang, Ye, Li, Zengyao, Huang, Longchang, Xin, Taojian, Shen, Renhui, Wang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889448/
https://www.ncbi.nlm.nih.gov/pubmed/33665222
http://dx.doi.org/10.1016/j.omtm.2020.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889448/
https://www.ncbi.nlm.nih.gov/pubmed/33665222
http://dx.doi.org/10.1016/j.omtm.2020.12.013

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