Anti-PD-1 antibody increases NK cell cytotoxicity towards nasopharyngeal carcinoma cells in the context of chemotherapy-induced upregulation of PD-1 and PD-L1

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a highly malignant epithelial cancer linked to Epstein–Barr virus (EBV) infection. Tumors are characterized by a lymphomononuclear infiltrate and the number of natural killer (NK) cells in tumors appears to be of prognostic significance. Standard treatme...

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Detalles Bibliográficos
Autores principales: Makowska, Anna, Meier, Selina, Shen, Lian, Busson, Pierre, Baloche, Valentin, Kontny, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889576/
https://www.ncbi.nlm.nih.gov/pubmed/32737537
http://dx.doi.org/10.1007/s00262-020-02681-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889576/
https://www.ncbi.nlm.nih.gov/pubmed/32737537
http://dx.doi.org/10.1007/s00262-020-02681-x

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