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Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla

The thymus’ key function in the immune system is to provide the necessary environment for the development of diverse and self-tolerant T lymphocytes. While recent evidence suggests that the thymic stroma is comprised of more functionally distinct subpopulations than previously appreciated, the exten...

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Detalles Bibliográficos
Autores principales: Bautista, Jhoanne L., Cramer, Nathan T., Miller, Corey N., Chavez, Jessica, Berrios, David I., Byrnes, Lauren E., Germino, Joe, Ntranos, Vasilis, Sneddon, Julie B., Burt, Trevor D., Gardner, James M., Ye, Chun J., Anderson, Mark S., Parent, Audrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889611/
https://www.ncbi.nlm.nih.gov/pubmed/33597545
http://dx.doi.org/10.1038/s41467-021-21346-6