Cargando…

Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model

Adjuvant ultrasound at 2 MHz with or without an ultrasound contrast agent improves the rate of thrombus resolution by recombinant tissue plasminogen activator (rt-PA) in laboratory and clinical studies. A sub-megahertz approach can further expand this therapy to a subset of patients with an insuffic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kleven, Robert T., Karani, Kunal B., Hilvert, Nicole, Ford, Samantha M., Mercado-Shekhar, Karla P., Racadio, John M., Rao, Marepalli B., Abruzzo, Todd A., Holland, Christy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889614/
https://www.ncbi.nlm.nih.gov/pubmed/33597659
http://dx.doi.org/10.1038/s41598-021-83442-3