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A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans

The four-dengue virus (DENV) serotypes infect several hundred million people annually. For the greatest safety and efficacy, tetravalent DENV vaccines are designed to stimulate balanced protective immunity to all four serotypes. However, this has been difficult to achieve. Clinical trials with a lea...

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Detalles Bibliográficos
Autores principales: Nivarthi, Usha K., Swanstrom, Jesica, Delacruz, Matthew J., Patel, Bhumi, Durbin, Anna P., Whitehead, Steve S., Kirkpatrick, Beth D., Pierce, Kristen K., Diehl, Sean A., Katzelnick, Leah, Baric, Ralph S., de Silva, Aravinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889627/
https://www.ncbi.nlm.nih.gov/pubmed/33597521
http://dx.doi.org/10.1038/s41467-021-21384-0