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Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer

BACKGROUND: At diagnosis, tumor-infiltrating lymphocytes (TILs) are prognostic in epithelial ovarian cancer (EOC). We recently demonstrated that neoadjuvant chemotherapy (NACT) significantly increased stromal TILs. Here, we investigated the impact of NACT on immune subpopulations with a particular f...

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Detalles Bibliográficos
Autores principales: Leary, Alexandra, Genestie, Catherine, Blanc-Durand, Félix, Gouy, Sébastien, Dunant, Ariane, Maulard, Amandine, Drusch, Françoise, Cheaib, Bianca, Michels, Judith, Bentivegna, Enrica, LeFormal, Audrey, Mesnage, Soizick, Morice, Philippe, Pautier, Patricia, Khairallah, Aya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889679/
https://www.ncbi.nlm.nih.gov/pubmed/32852603
http://dx.doi.org/10.1007/s00262-020-02670-0