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Rapid whole cell imaging reveals a calcium-APPL1-dynein nexus that regulates cohort trafficking of stimulated EGF receptors

The endosomal system provides rich signal processing capabilities for responses elicited by growth factor receptors and their ligands. At the single cell level, endosomal trafficking becomes a critical component of signal processing, as exemplified by the epidermal growth factor (EGF) receptors. Act...

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Detalles Bibliográficos
Autores principales: York, H. M., Patil, A., Moorthi, U. K., Kaur, A., Bhowmik, A., Hyde, G. J., Gandhi, H., Fulcher, A., Gaus, K., Arumugam, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889693/
https://www.ncbi.nlm.nih.gov/pubmed/33597720
http://dx.doi.org/10.1038/s42003-021-01740-y