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Cell-type specific asynchronous modulation of PKA by dopamine in learning

Reinforcement learning models postulate that dopamine (DA) releasing neurons (DANs) encode information about action and action outcome and provide a teaching signal to striatal spiny projection neurons (SPNs) in the form of DA release(1). DA is thought to guide learning via dynamic and differential...

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Detalles Bibliográficos
Autores principales: Lee, Suk Joon, Lodder, Bart, Chen, Yao, Patriarchi, Tommaso, Tian, Lin, Sabatini, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889726/
https://www.ncbi.nlm.nih.gov/pubmed/33361810
http://dx.doi.org/10.1038/s41586-020-03050-5