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Active-site loop variations adjust activity and selectivity of the cumene dioxygenase
Active-site loops play essential roles in various catalytically important enzyme properties like activity, selectivity, and substrate scope. However, their high flexibility and diversity makes them challenging to incorporate into rational enzyme engineering strategies. Here, we report the engineerin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889853/ https://www.ncbi.nlm.nih.gov/pubmed/33597523 http://dx.doi.org/10.1038/s41467-021-21328-8 |