CD4+ T cells from children with active juvenile idiopathic arthritis show altered chromatin features associated with transcriptional abnormalities

Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases in children. While clinical outcomes for patients with juvenile JIA have improved, the underlying biology of the disease and mechanisms underlying therapeutic response/non-response are poorly understood. We have shown tha...

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Detalles Bibliográficos
Autores principales: Tarbell, Evan, Jiang, Kaiyu, Hennon, Teresa R., Holmes, Lucy, Williams, Sonja, Fu, Yao, Gaffney, Patrick M., Liu, Tao, Jarvis, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889855/
https://www.ncbi.nlm.nih.gov/pubmed/33597588
http://dx.doi.org/10.1038/s41598-021-82989-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889855/
https://www.ncbi.nlm.nih.gov/pubmed/33597588
http://dx.doi.org/10.1038/s41598-021-82989-5

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