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Role of adenomatous polyposis coli in proliferation and differentiation of colon epithelial cells in organoid culture
Adenomatous polyposis coli (APC) is a tumor-suppressing protein whose inactivation triggers the formation of colorectal polyps. Numerous studies using cell lines or genetically engineered mice have revealed its role in suppressing Wnt/β-catenin signaling pathway and regulating cell proliferation and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889860/ https://www.ncbi.nlm.nih.gov/pubmed/33597597 http://dx.doi.org/10.1038/s41598-021-83590-6 |