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Role of adenomatous polyposis coli in proliferation and differentiation of colon epithelial cells in organoid culture

Adenomatous polyposis coli (APC) is a tumor-suppressing protein whose inactivation triggers the formation of colorectal polyps. Numerous studies using cell lines or genetically engineered mice have revealed its role in suppressing Wnt/β-catenin signaling pathway and regulating cell proliferation and...

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Detalles Bibliográficos
Autores principales:	Yamazaki, Daisuke, Hashizume, Osamu, Taniguchi, Shiho, Funato, Yosuke, Miki, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889860/ https://www.ncbi.nlm.nih.gov/pubmed/33597597 http://dx.doi.org/10.1038/s41598-021-83590-6

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