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The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2

NKCC and KCC transporters mediate coupled transport of Na(+)+K(+)+Cl(−) and K(+)+Cl(−) across the plasma membrane, thus regulating cell Cl(−) concentration and cell volume and playing critical roles in transepithelial salt and water transport and in neuronal excitability. The function of these trans...

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Detalles Bibliográficos
Autores principales: Zhang, Sensen, Zhou, Jun, Zhang, Yuebin, Liu, Tianya, Friedel, Perrine, Zhuo, Wei, Somasekharan, Suma, Roy, Kasturi, Zhang, Laixing, Liu, Yang, Meng, Xianbin, Deng, Haiteng, Zeng, Wenwen, Li, Guohui, Forbush, Biff, Yang, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889885/
https://www.ncbi.nlm.nih.gov/pubmed/33597714
http://dx.doi.org/10.1038/s42003-021-01750-w