Low-coverage whole-genome sequencing of extracellular vesicle-associated DNA in patients with metastatic cancer

Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (EV) represent a novel liquid biopsy source of tumoral DNA. This study compared copy number alteration (CNA) profiles generated from LC-WGS of formalin-fixed paraffin-embe...

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Detalles Bibliográficos
Autores principales: Nguyen, Bella, Wong, Nicholas C., Semple, Tim, Clark, Michael, Wong, Stephen Q., Leslie, Connull, Mirzai, Bob, Millward, Michael, Meehan, Katie, Lim, Annette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889887/
https://www.ncbi.nlm.nih.gov/pubmed/33597619
http://dx.doi.org/10.1038/s41598-021-83436-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889887/
https://www.ncbi.nlm.nih.gov/pubmed/33597619
http://dx.doi.org/10.1038/s41598-021-83436-1

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