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Low-coverage whole-genome sequencing of extracellular vesicle-associated DNA in patients with metastatic cancer
Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (EV) represent a novel liquid biopsy source of tumoral DNA. This study compared copy number alteration (CNA) profiles generated from LC-WGS of formalin-fixed paraffin-embe...
Autores principales: | Nguyen, Bella, Wong, Nicholas C., Semple, Tim, Clark, Michael, Wong, Stephen Q., Leslie, Connull, Mirzai, Bob, Millward, Michael, Meehan, Katie, Lim, Annette M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889887/ https://www.ncbi.nlm.nih.gov/pubmed/33597619 http://dx.doi.org/10.1038/s41598-021-83436-1 |
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