Determinants of genome-wide distribution and evolution of uORFs in eukaryotes

Upstream open reading frames (uORFs) play widespread regulatory functions in modulating mRNA translation in eukaryotes, but the principles underlying the genomic distribution and evolution of uORFs remain poorly understood. Here, we analyze ~17 million putative canonical uORFs in 478 eukaryotic spec...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Wang, Yirong, Wu, Xinkai, Tang, Xiaolu, Wu, Changcheng, Lu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889888/
https://www.ncbi.nlm.nih.gov/pubmed/33597535
http://dx.doi.org/10.1038/s41467-021-21394-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889888/
https://www.ncbi.nlm.nih.gov/pubmed/33597535
http://dx.doi.org/10.1038/s41467-021-21394-y

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