Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis

Lumbar spinal canal stenosis (LSS) or mechanical compression of dorsal root ganglion (DRG) is one of the causes of low back pain and neuropathic pain (NP). Lysophosphatidic acid (LPA) is a potent bioactive lipid mediator that is produced mainly from lysophosphatidylcholine (LPC) via autotaxin (ATX)...

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Detalles Bibliográficos
Autores principales: Uranbileg, Baasanjav, Ito, Nobuko, Kurano, Makoto, Kano, Kuniyuki, Uchida, Kanji, Sumitani, Masahiko, Aoki, Junken, Yatomi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889906/
https://www.ncbi.nlm.nih.gov/pubmed/33597645
http://dx.doi.org/10.1038/s41598-021-83569-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889906/
https://www.ncbi.nlm.nih.gov/pubmed/33597645
http://dx.doi.org/10.1038/s41598-021-83569-3

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