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PTEN Reduces BMP9-Induced Osteogenic Differentiation Through Inhibiting Wnt10b in Mesenchymal Stem Cells

Bone morphogenetic protein 9 (BMP9) is one of the most efficacious osteogenic cytokines. PTEN and Wnt10b are both implicated in regulating the osteogenic potential of BMP9, but the potential relationship between them is unknown. In this study, we determined whether PTEN could reduce the expression o...

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Detalles Bibliográficos
Autores principales: Li, Fu-Shu, Li, Pei-Pei, Li, Ling, Deng, Yan, Hu, Ying, He, Bai-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889951/
https://www.ncbi.nlm.nih.gov/pubmed/33614622
http://dx.doi.org/10.3389/fcell.2020.608544