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Bringing a Gene-Activated Bone Substitute Into Clinical Practice: From Bench to Bedside

Bone grafting and reconstruction are still challenging in clinical practice because of the limitations of bone autografts and the drawbacks of currently approved bone substitutes. We thus developed a gene-activated bone substitute based on octacalcium phosphate and naked plasmid DNA carrying the vas...

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Detalles Bibliográficos
Autores principales: Bozo, Ilia Y., Drobyshev, Alexey Y., Redko, Nikolay A., Komlev, Vladimir S., Isaev, Artur A., Deev, Roman V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889956/
https://www.ncbi.nlm.nih.gov/pubmed/33614609
http://dx.doi.org/10.3389/fbioe.2021.599300