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Bringing a Gene-Activated Bone Substitute Into Clinical Practice: From Bench to Bedside
Bone grafting and reconstruction are still challenging in clinical practice because of the limitations of bone autografts and the drawbacks of currently approved bone substitutes. We thus developed a gene-activated bone substitute based on octacalcium phosphate and naked plasmid DNA carrying the vas...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889956/ https://www.ncbi.nlm.nih.gov/pubmed/33614609 http://dx.doi.org/10.3389/fbioe.2021.599300 |