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Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-β1 Signaling Pathways

It is well-known that all progressive chronic kidney disease (CKD) is pathologically characterized by tubulointerstitial fibrosis process. Multiple studies have shown the critical role of inflammation and fibrosis in the development of CKD. Hence strategies that target inflammatory and fibrotic sign...

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Detalles Bibliográficos
Autores principales: Yi, Hao, Huang, Chunling, Shi, Ying, Cao, Qinghua, Chen, Jason, Chen, Xin-Ming, Pollock, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889967/
https://www.ncbi.nlm.nih.gov/pubmed/33614642
http://dx.doi.org/10.3389/fcell.2021.603802