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Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke

Exosomes contribute to cell–cell communications. Emerging evidence has shown that microglial exosomes may play crucial role in regulation of neuronal functions under ischemic conditions. However, the underlying mechanisms of microglia-derived exosome biosynthesis are largely unknown. Herein, we repo...

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Detalles Bibliográficos
Autores principales: Zang, Jiankun, Wu, Yousheng, Su, Xuanlin, Zhang, Tianyuan, Tang, Xionglin, Ma, Dan, Li, Yufeng, Liu, Yanfang, Weng, Ze’an, Liu, Xuanzhuo, Tsang, Chi Kwan, Xu, Anding, Lu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889976/
https://www.ncbi.nlm.nih.gov/pubmed/33614626
http://dx.doi.org/10.3389/fcell.2020.616590