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FLICK: an optimized plate reader-based assay to infer cell death kinetics
Evaluating drug sensitivity is improved by directly quantifying death kinetics, rather than correlates of viability, such as metabolic activity. This is challenging, requiring time-lapse microscopy and genetically encoded labels to distinguish live and dead cells. Here, we describe fluorescence-base...
Autores principales: | Richards, Ryan, Honeywell, Megan E., Lee, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890003/ https://www.ncbi.nlm.nih.gov/pubmed/33659903 http://dx.doi.org/10.1016/j.xpro.2021.100327 |
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