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A20 Inhibits Intraocular Inflammation in Mice by Regulating the Function of CD4+T Cells and RPE Cells

A20 is a negative regulator of inflammation and immunity and plays a role in several autoimmune and inflammatory diseases. Here, we demonstrate that A20 overexpression significantly ameliorates severity of EAU by inhibiting the infiltration of Th1 and Th17 cells, and by protecting integrity of the b...

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Detalles Bibliográficos
Autores principales: Hu, Jianping, Yi, Shenglan, Wang, Chaokui, Zhang, Yiting, Tang, Jihong, Huang, Xinyue, Yang, Lu, Yang, Jinglu, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890008/
https://www.ncbi.nlm.nih.gov/pubmed/33613524
http://dx.doi.org/10.3389/fimmu.2020.603939