Mechanical stretch induces Ca(2+) influx and extracellular release of PGE(2) through Piezo1 activation in trabecular meshwork cells

The trabecular meshwork (TM) constitutes the main pathway for aqueous humor drainage and is exposed to complex intraocular pressure fluctuations. The mechanism of homeostasis in which TM senses changes in intraocular pressure and leads to normal levels of outflow resistance is not yet well understoo...

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Detalles Bibliográficos
Autores principales: Uchida, Takatoshi, Shimizu, Shota, Yamagishi, Reiko, Tokuoka, Suzumi M., Kita, Yoshihiro, Honjo, Megumi, Aihara, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890064/
https://www.ncbi.nlm.nih.gov/pubmed/33597646
http://dx.doi.org/10.1038/s41598-021-83713-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890064/
https://www.ncbi.nlm.nih.gov/pubmed/33597646
http://dx.doi.org/10.1038/s41598-021-83713-z

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