Cargando…
Mechanical stretch induces Ca(2+) influx and extracellular release of PGE(2) through Piezo1 activation in trabecular meshwork cells
The trabecular meshwork (TM) constitutes the main pathway for aqueous humor drainage and is exposed to complex intraocular pressure fluctuations. The mechanism of homeostasis in which TM senses changes in intraocular pressure and leads to normal levels of outflow resistance is not yet well understoo...
Autores principales: | Uchida, Takatoshi, Shimizu, Shota, Yamagishi, Reiko, Tokuoka, Suzumi M., Kita, Yoshihiro, Honjo, Megumi, Aihara, Makoto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890064/ https://www.ncbi.nlm.nih.gov/pubmed/33597646 http://dx.doi.org/10.1038/s41598-021-83713-z |
Ejemplares similares
-
TRPV4 is activated by mechanical stimulation to induce prostaglandins release in trabecular meshwork, lowering intraocular pressure
por: Uchida, Takatoshi, et al.
Publicado: (2021) -
Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma
por: Igarashi, Nozomi, et al.
Publicado: (2021) -
Effects of selective EP2 receptor agonist, omidenepag, on trabecular meshwork cells, Schlemm’s canal endothelial cells and ciliary muscle contraction
por: Nakamura, Natsuko, et al.
Publicado: (2021) -
Effect of pigmentation intensity of trabecular meshwork cells on mechanisms of micropulse laser trabeculoplasty
por: Shimizu, Shota, et al.
Publicado: (2022) -
Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor
por: Liu, Mengxuan, et al.
Publicado: (2022)