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Quinolinate Phosphoribosyltransferase Promotes Invasiveness of Breast Cancer Through Myosin Light Chain Phosphorylation
Perturbed Nicotinamide adenine dinucleotide (NAD(+)) homeostasis is involved in cancer progression and metastasis. Quinolinate phosphoribosyltransferase (QPRT) is the rate-limiting enzyme in the kynurenine pathway participating in NAD(+) generation. In this study, we demonstrated that QPRT expressio...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890081/ https://www.ncbi.nlm.nih.gov/pubmed/33613454 http://dx.doi.org/10.3389/fendo.2020.621944 |