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Quinolinate Phosphoribosyltransferase Promotes Invasiveness of Breast Cancer Through Myosin Light Chain Phosphorylation

Perturbed Nicotinamide adenine dinucleotide (NAD(+)) homeostasis is involved in cancer progression and metastasis. Quinolinate phosphoribosyltransferase (QPRT) is the rate-limiting enzyme in the kynurenine pathway participating in NAD(+) generation. In this study, we demonstrated that QPRT expressio...

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Detalles Bibliográficos
Autores principales:	Liu, Chien-Liang, Cheng, Shih-Ping, Chen, Ming-Jen, Lin, Chi-Hsin, Chen, Shan-Na, Kuo, Yi-Hue, Chang, Yuan-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890081/ https://www.ncbi.nlm.nih.gov/pubmed/33613454 http://dx.doi.org/10.3389/fendo.2020.621944

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