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The Efficacy and Safety of the mTOR Signaling Pathway Activator, MHY1485, for in vitro Activation of Human Ovarian Tissue

BACKGROUND: Premature ovarian insufficiency (POI) is characterized by abnormal ovarian function before the age of 40. POI showed that primordial follicles developed in disorder. mTOR signaling plays a vital role in the process of follicle development. It has been verified that the mTOR signaling pat...

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Detalles Bibliográficos
Autores principales: Wu, Shuang, Wang, Yining, Ding, Haixiang, Sun, Ningxia, Liu, Yan, Wang, Liang, Sheng, Fei, Zhang, Honghong, Yang, Fu, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890121/
https://www.ncbi.nlm.nih.gov/pubmed/33613618
http://dx.doi.org/10.3389/fgene.2020.603683