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Chemotherapy triggers cachexia by deregulating synergetic function of histone‐modifying enzymes

BACKGROUND: Chemotherapy is the first line of treatment for cancer patients. However, the side effects cause severe muscle atrophy or chemotherapy‐induced cachexia. Previously, the NF‐κB/MuRF1‐dependent pathway was shown to induce chemotherapy‐induced cachexia. We hypothesized that acute collateral...

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Detalles Bibliográficos
Autores principales: Amrute‐Nayak, Mamta, Pegoli, Gloria, Holler, Tim, Lopez‐Davila, Alfredo Jesus, Lanzuolo, Chiara, Nayak, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890149/
https://www.ncbi.nlm.nih.gov/pubmed/33305533
http://dx.doi.org/10.1002/jcsm.12645