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In silico designing of putative peptides for targeting pathological protein Htt in Huntington's disease
Huntington's disease is a neurodegenerative disease caused by CAG repeat in the first exon of HTT (Huntingtin) gene, leading to abnormal form of Htt protein containing enlarged polyglutamine strands of variable length that stick together to form aggregates and is toxic to brain causing brain da...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890153/ https://www.ncbi.nlm.nih.gov/pubmed/33659724 http://dx.doi.org/10.1016/j.heliyon.2021.e06088 |