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Treatment of contaminated radial fracture in Sprague-Dawley rats by application of a degradable polymer releasing gentamicin

Fracture-related infections remain a leading cause of morbidity and mortality. We aimed to establish a simple contaminated radial osteotomy model to assess the efficacy of a biodegradable polymer poly(sebacic-co-ricinoleic acid) [p(SA-RA)] containing 20% w/w gentamicin. A unilateral transverse osteo...

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Detalles Bibliográficos
Autores principales: Ramot, Yuval, Steiner, Michal, Amouyal, Netanel, Lavie, Yossi, Klaiman, Guy, Domb, Abraham J., Nyska, Abraham, Hagigit, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890171/
https://www.ncbi.nlm.nih.gov/pubmed/33627941
http://dx.doi.org/10.1293/tox.2020-0041