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CAR-T cells for Colorectal Cancer: Target-selection and strategies for improved activity and safety

Chimeric antigen receptor-T (CAR-T) cell immunotherapy is a novel method that is genetically engineered to recruit T cells against malignant disease. Administration of CAR-T cells has led to progress in hematological malignancies, and it has been proposed for solid tumors like colorectal cancer (CRC...

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Detalles Bibliográficos
Autores principales: Li, Huali, Yang, Chao, Cheng, Huangrong, Huang, Shuoyang, Zheng, Yongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890323/
https://www.ncbi.nlm.nih.gov/pubmed/33613769
http://dx.doi.org/10.7150/jca.50509