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iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy

Adenovirus-mediated combination gene therapies have shown promising results in vaccination or treating malignant and genetic diseases. Nevertheless, an efficient system for the rapid assembly and incorporation of therapeutic genes into high-capacity adenoviral vectors (HCAdVs) is still missing. In t...

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Detalles Bibliográficos
Autores principales: Brücher, Dominik, Kirchhammer, Nicole, Smith, Sheena N., Schumacher, Jatina, Schumacher, Nina, Kolibius, Jonas, Freitag, Patrick C., Schmid, Markus, Weiss, Fabian, Keller, Corina, Grove, Melanie, Greber, Urs F., Zippelius, Alfred, Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890373/
https://www.ncbi.nlm.nih.gov/pubmed/33665227
http://dx.doi.org/10.1016/j.omtm.2021.01.002