Tumour extracellular vesicle‐derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement‐dependent cytotoxicity of tumour cells

The complement system is involved in the immunosurveillance of pathogens and tumour cells. Proteomic profiling revealed that extracellular vesicles (EVs) released by metastatic hepatocellular carcinoma (HCC) cells contained a significant number of complement proteins. Complement Factor H (CFH), an a...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Xiaowen, Zhou, Longyin, Tey, Sze Keong, Ma, Angel Po Yee, Yeung, Cherlie Lot Sum, Ng, Tung Him, Wong, Samuel Wan Ki, Liu, Bonnie Hei Man, Fung, Yi Man Eva, Patz, Edward F., Cao, Peihua, Gao, Yi, Yam, Judy Wai Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890557/
https://www.ncbi.nlm.nih.gov/pubmed/33708358
http://dx.doi.org/10.1002/jev2.12031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890557/
https://www.ncbi.nlm.nih.gov/pubmed/33708358
http://dx.doi.org/10.1002/jev2.12031

Ejemplares similares