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Tumour extracellular vesicle‐derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement‐dependent cytotoxicity of tumour cells
The complement system is involved in the immunosurveillance of pathogens and tumour cells. Proteomic profiling revealed that extracellular vesicles (EVs) released by metastatic hepatocellular carcinoma (HCC) cells contained a significant number of complement proteins. Complement Factor H (CFH), an a...
Autores principales: | Mao, Xiaowen, Zhou, Longyin, Tey, Sze Keong, Ma, Angel Po Yee, Yeung, Cherlie Lot Sum, Ng, Tung Him, Wong, Samuel Wan Ki, Liu, Bonnie Hei Man, Fung, Yi Man Eva, Patz, Edward F., Cao, Peihua, Gao, Yi, Yam, Judy Wai Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890557/ https://www.ncbi.nlm.nih.gov/pubmed/33708358 http://dx.doi.org/10.1002/jev2.12031 |
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