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Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers

BACKGROUND: Natural products are a valuable source of biologically active compounds that have applications in medicine and agriculture. One disadvantage with natural products is the slow, time-consuming strain improvement regimes that are necessary to ensure sufficient quantities of target compounds...

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Detalles Bibliográficos
Autores principales: Pikl, Špela, Rincón, Andrés Felipe Carrillo, Slemc, Lucija, Goranovič, Dušan, Avbelj, Martina, Gjuračić, Krešimir, Sucipto, Hilda, Stare, Katja, Baebler, Špela, Šala, Martin, Guo, Meijin, Luzhetskyy, Andriy, Petković, Hrvoje, Magdevska, Vasilka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890619/
https://www.ncbi.nlm.nih.gov/pubmed/33596911
http://dx.doi.org/10.1186/s12934-021-01522-5